MLB Game Previews | Wednesday, July 22, 2026

The daily card in bettor-friendly language: what LyDia likes, what it does not, and the actual reason behind each decision.

GAMES
17
OFFICIAL PICKS
1
VALUE WATCH
1
WATCHLIST
5
PASSES
10

Updated Jul 22, 11:24 AM EDT. Official picks are published before grading.

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Cincinnati Reds @ Seattle Mariners

3:40 PM ET · Brady Singer vs Emerson Hancock
Value Watch
LyDia side
Seattle Mariners Money Line
Lab Rating
9.1/10
Model probability
66.1%
Market probability
58.4%
Model vs market
+7.8%
Current price
-150
Pitcher edge
Seattle Mariners by 20 points
Bullpen read
Bullpen workload is elevated but not decisive. Seattle Mariners is 6.5/10 and Cincinnati Reds is 5.3/10.
Why LyDia made this decisionSeattle Mariners grades as a strong value setup with 66.1% model win probability against a 58.4% market number and a 9.1/10 Lab Rating. Seattle Mariners has the stronger starting pitcher matchup by 20 rating points. Seattle Mariners has the lower-risk bullpen, 5.1/10 versus 7.4/10. Cincinnati Reds has 9.0 relief innings over the last three days, 1 back-to-back arm. Cincinnati Reds's pen has been struggling lately (0.9/10 efficiency). Bullpen fatigue moved this probability up 1.6 points from 64.6% (starting pitcher and team strength only) to 66.1%. It stayed a value watch because model win probability is 66.1%, below the 72.0% official-pick gate.
Risk noteNo model can see every live lineup, injury, or late bullpen availability update. Recheck official news before first pitch.

Baltimore Orioles @ Boston Red Sox

1:35 PM ET · Dean Kremer vs Jake Bennett
Official Pick
LyDia side
Boston Red Sox Money Line
Lab Rating
8.1/10
Model probability
73.0%
Market probability
56.1%
Model vs market
+16.9%
Current price
-135
Pitcher edge
Boston Red Sox by 13 points
Bullpen read
Bullpen workload is elevated but not decisive. Boston Red Sox is 6.1/10 and Baltimore Orioles is 5.7/10.
Why LyDia made this decisionBoston Red Sox is an official moneyline pick because LyDia gives it a 73.0% chance to win, compared with the market's 56.1% no-vig probability. The full setup earned a 8.1/10 Lab Rating. Boston Red Sox has the stronger starting pitcher matchup by 13 rating points. Bullpen risk is elevated but not decisive. Boston Red Sox is 5.3/10 and Baltimore Orioles is 6.2/10. At -135, the price still offers enough value for the play to qualify as official.
Risk noteNo model can see every live lineup, injury, or late bullpen availability update. Recheck official news before first pitch.

Los Angeles Dodgers @ Philadelphia Phillies

6:40 PM ET · Eric Lauer vs Aaron Nola
Watchlist
LyDia side
Los Angeles Dodgers Money Line
Lab Rating
7.2/10
Model probability
61.4%
Market probability
52.6%
Model vs market
+8.9%
Current price
-117
Pitcher edge
Los Angeles Dodgers by 5 points
Bullpen read
Los Angeles Dodgers has the fresher bullpen, 5.3/10 versus 7.0/10. Philadelphia Phillies has used 10.7 bullpen innings over the last three days with 3 back-to-back arms.
Why LyDia made this decisionLos Angeles Dodgers is worth monitoring, but it does not clear every requirement for an official pick. LyDia projects 61.4% win probability, the market is at 52.6%, and the setup carries a 7.2/10 Lab Rating. Los Angeles Dodgers has the stronger starting pitcher matchup by 5 rating points. Los Angeles Dodgers has the lower-risk bullpen, 5.4/10 versus 7.3/10. Philadelphia Phillies has 10.7 relief innings over the last three days, 3 back-to-back arms. Philadelphia Phillies's pen has been below average lately (4.4/10 efficiency). Bullpen fatigue moved this probability up 1.4 points from 60.1% (starting pitcher and team strength only) to 61.4%.
Risk noteNo model can see every live lineup, injury, or late bullpen availability update. Recheck official news before first pitch.

San Diego Padres @ Atlanta Braves

7:15 PM ET · Michael King vs Martín Pérez
Watchlist
LyDia side
Atlanta Braves Money Line
Lab Rating
6.8/10
Model probability
64.4%
Market probability
51.3%
Model vs market
+13.1%
Current price
-108
Pitcher edge
No clear SP edge by 3 points
Bullpen read
Bullpen workload is elevated but not decisive. Atlanta Braves is 7.4/10 and San Diego Padres is 7.0/10.
Why LyDia made this decisionAtlanta Braves is worth monitoring, but it does not clear every requirement for an official pick. LyDia projects 64.4% win probability, the market is at 51.3%, and the setup carries a 6.8/10 Lab Rating. The starting pitching matchup does not create a clear advantage. Bullpen risk is elevated but not decisive. Atlanta Braves is 7.3/10 and San Diego Padres is 5.9/10.
Risk noteNo model can see every live lineup, injury, or late bullpen availability update. Recheck official news before first pitch.

Baltimore Orioles @ Boston Red Sox

7:10 PM ET · Kyle Bradish vs TBD
Watchlist
LyDia side
Boston Red Sox Money Line
Lab Rating
6.7/10
Model probability
64.4%
Market probability
56.1%
Model vs market
+8.4%
Current price
-135
Pitcher edge
Baltimore Orioles by 14 points
Bullpen read
Bullpen workload is elevated but not decisive. Boston Red Sox is 6.1/10 and Baltimore Orioles is 5.7/10.
Why LyDia made this decisionBoston Red Sox is worth monitoring, but it does not clear every requirement for an official pick. LyDia projects 64.4% win probability, the market is at 56.1%, and the setup carries a 6.7/10 Lab Rating. Baltimore Orioles has the starting pitcher advantage by 14 rating points, which works against LyDia's side. Bullpen risk is elevated but not decisive. Boston Red Sox is 5.3/10 and Baltimore Orioles is 6.2/10.
Risk notePrimary caution: starting pitcher edge conflicts with the model side. Recheck official news before first pitch.

Minnesota Twins @ Cleveland Guardians

6:40 PM ET · Bailey Ober vs Slade Cecconi
Watchlist
LyDia side
Cleveland Guardians Money Line
Lab Rating
6.6/10
Model probability
62.8%
Market probability
53.5%
Model vs market
+9.2%
Current price
-121
Pitcher edge
Minnesota Twins by 6 points
Bullpen read
Bullpen workload is elevated but not decisive. Cleveland Guardians is 7.6/10 and Minnesota Twins is 7.5/10.
Why LyDia made this decisionCleveland Guardians is worth monitoring, but it does not clear every requirement for an official pick. LyDia projects 62.8% win probability, the market is at 53.5%, and the setup carries a 6.6/10 Lab Rating. Minnesota Twins has the starting pitcher advantage by 6 rating points, which works against LyDia's side. Bullpen risk is elevated but not decisive. Cleveland Guardians is 7.8/10 and Minnesota Twins is 8.1/10.
Risk noteNo model can see every live lineup, injury, or late bullpen availability update. Recheck official news before first pitch.

Miami Marlins @ Houston Astros

8:10 PM ET · Sandy Alcantara vs Peter Lambert
Watchlist
LyDia side
Houston Astros Money Line
Lab Rating
6.6/10
Model probability
58.7%
Market probability
52.3%
Model vs market
+6.5%
Current price
-115
Pitcher edge
Houston Astros by 8 points
Bullpen read
Bullpen workload is elevated but not decisive. Houston Astros is 7.0/10 and Miami Marlins is 6.0/10.
Why LyDia made this decisionHouston Astros is worth monitoring, but it does not clear every requirement for an official pick. LyDia projects 58.7% win probability, the market is at 52.3%, and the setup carries a 6.6/10 Lab Rating. Houston Astros has the stronger starting pitcher matchup by 8 rating points. Bullpen risk is elevated but not decisive. Houston Astros is 6.7/10 and Miami Marlins is 6.6/10.
Risk noteNo model can see every live lineup, injury, or late bullpen availability update. Recheck official news before first pitch.

New York Mets @ Milwaukee Brewers

2:10 PM ET · Christian Scott vs Logan Henderson
Pass
LyDia side
Milwaukee Brewers Money Line
Lab Rating
6.4/10
Model probability
65.4%
Market probability
56.2%
Model vs market
+9.2%
Current price
-133
Pitcher edge
Milwaukee Brewers by 5 points
Bullpen read
Milwaukee Brewers carries the heavier bullpen workload, 7.5/10 versus 4.5/10, which adds late-game risk. Milwaukee Brewers has used 13.3 bullpen innings over the last three days with 4 back-to-back arms.
Why LyDia made this decisionThe combined Lab Rating did not clear the official threshold.
Pass reasonThe combined Lab Rating did not clear the official threshold.

Athletics @ Arizona Diamondbacks

3:40 PM ET · Gage Jump vs Merrill Kelly
Pass
LyDia side
Arizona Diamondbacks Money Line
Lab Rating
6.1/10
Model probability
65.5%
Market probability
54.2%
Model vs market
+11.3%
Current price
-124
Pitcher edge
Athletics by 15 points
Bullpen read
Both bullpens are heavily taxed. Arizona Diamondbacks is 8.6/10 and Athletics is 8.3/10, so late-game volatility is elevated on both sides.
Why LyDia made this decisionStarting pitcher edge conflicts with the model side.
Pass reasonStarting pitcher edge conflicts with the model side.

Tampa Bay Rays @ Toronto Blue Jays

7:07 PM ET · Griffin Jax vs Braydon Fisher
Pass
LyDia side
Tampa Bay Rays Money Line
Lab Rating
5.8/10
Model probability
53.8%
Market probability
49.7%
Model vs market
+4.1%
Current price
-102
Pitcher edge
No clear SP edge by 3 points
Bullpen read
Bullpen workload is elevated but not decisive. Tampa Bay Rays is 5.8/10 and Toronto Blue Jays is 6.4/10.
Why LyDia made this decisionThe combined Lab Rating did not clear the official threshold.
Pass reasonThe combined Lab Rating did not clear the official threshold.

Pittsburgh Pirates @ New York Yankees

7:05 PM ET · Bubba Chandler vs Max Fried
Pass
LyDia side
New York Yankees Money Line
Lab Rating
5.1/10
Model probability
62.6%
Market probability
60.3%
Model vs market
+2.3%
Current price
-160
Pitcher edge
New York Yankees by 21 points
Bullpen read
New York Yankees carries the heavier bullpen workload, 8.2/10 versus 6.6/10, which adds late-game risk. New York Yankees has used 15.3 bullpen innings over the last three days with 4 back-to-back arms.
Why LyDia made this decisionModel and market are too close for a clear official pick.
Pass reasonModel and market are too close for a clear official pick.

St. Louis Cardinals @ Los Angeles Angels

4:07 PM ET · Hunter Dobbins vs Reid Detmers
Pass
LyDia side
Los Angeles Angels Money Line
Lab Rating
3.8/10
Model probability
54.0%
Market probability
54.6%
Model vs market
-0.6%
Current price
-127
Pitcher edge
Los Angeles Angels by 12 points
Bullpen read
No meaningful bullpen fatigue edge — both pens come in comparable (Los Angeles Angels 5.3/10, St. Louis Cardinals 5.9/10).
Why LyDia made this decisionMarket is higher than LyDia's model probability.
Pass reasonMarket is higher than LyDia's model probability.

Chicago White Sox @ Texas Rangers

8:05 PM ET · Anthony Kay vs Tyler Alexander
Pass
LyDia side
Texas Rangers Money Line
Lab Rating
3.8/10
Model probability
51.7%
Market probability
49.9%
Model vs market
+1.8%
Current price
-105
Pitcher edge
Texas Rangers by 10 points
Bullpen read
Bullpen workload is elevated but not decisive. Texas Rangers is 7.4/10 and Chicago White Sox is 6.4/10.
Why LyDia made this decisionModel and market are too close for a clear official pick.
Pass reasonModel and market are too close for a clear official pick.

Pittsburgh Pirates @ New York Yankees

1:05 PM ET · Mitch Keller vs Gerrit Cole
Pass
LyDia side
New York Yankees Money Line
Lab Rating
3.4/10
Model probability
61.0%
Market probability
60.3%
Model vs market
+0.7%
Current price
-160
Pitcher edge
New York Yankees by 12 points
Bullpen read
New York Yankees carries the heavier bullpen workload, 8.2/10 versus 6.6/10, which adds late-game risk. New York Yankees has used 15.3 bullpen innings over the last three days with 4 back-to-back arms.
Why LyDia made this decisionModel and market are too close for a clear official pick.
Pass reasonModel and market are too close for a clear official pick.

Detroit Tigers @ Chicago Cubs

8:10 PM ET · Keider Montero vs Colin Rea
Pass
LyDia side
Chicago Cubs Money Line
Lab Rating
3.0/10
Model probability
52.8%
Market probability
52.8%
Model vs market
+0.0%
Current price
-118
Pitcher edge
Detroit Tigers by 21 points
Bullpen read
Chicago Cubs has the fresher bullpen, 4.8/10 versus 9.3/10. Detroit Tigers has used 18.7 bullpen innings over the last three days with 3 back-to-back arms.
Why LyDia made this decisionModel and market are too close for a clear official pick.
Pass reasonModel and market are too close for a clear official pick.

Washington Nationals @ Colorado Rockies

3:10 PM ET · Cade Cavalli vs Gabriel Hughes
Pass
LyDia side
Washington Nationals Money Line
Lab Rating
2.6/10
Model probability
56.4%
Market probability
56.4%
Model vs market
+0.1%
Current price
-137
Pitcher edge
No clear SP edge by 2 points
Bullpen read
Both bullpens are heavily taxed. Washington Nationals is 8.4/10 and Colorado Rockies is 7.9/10, so late-game volatility is elevated on both sides.
Why LyDia made this decisionModel and market are too close for a clear official pick.
Pass reasonModel and market are too close for a clear official pick.

San Francisco Giants @ Kansas City Royals

2:10 PM ET · Landen Roupp vs Seth Lugo
Pass
LyDia side
San Francisco Giants Money Line
Lab Rating
2.4/10
Model probability
51.3%
Market probability
54.5%
Model vs market
-3.1%
Current price
-126
Pitcher edge
San Francisco Giants by 6 points
Bullpen read
Bullpen workload is elevated but not decisive. San Francisco Giants is 7.0/10 and Kansas City Royals is 6.4/10.
Why LyDia made this decisionMarket is higher than LyDia's model probability.
Pass reasonMarket is higher than LyDia's model probability.

Model outputs, not promises. LyDia provides analysis and education only, not betting advice. Every official pick is graded on the Results page.